{"id":24,"date":"2019-09-17T13:23:12","date_gmt":"2019-09-17T13:23:12","guid":{"rendered":"http:\/\/rgdscience.com\/?page_id=24"},"modified":"2026-05-01T18:47:26","modified_gmt":"2026-05-01T17:47:26","slug":"consultancy","status":"publish","type":"page","link":"https:\/\/www.rgdscience.com\/index.php\/consultancy\/","title":{"rendered":"CONSULTANCY"},"content":{"rendered":"\n
<\/div>\n\n\n\n
<\/div><\/span>
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Drug Discovery consultancy expertise<\/h5>\n\n\n\n
<\/div>\n\n\n\n
\n
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Multiple disease areas<\/strong><\/h5>\n
    \n
  • Cancer \u2022 Neuroscience \u2022 Cardiovascular \u2022 Diseases of the developing world \u2022 Fibrotic diseases \u2022 Viruses \u2022 Inflammation \u2022 Respiratory diseases<\/li>\n<\/ul>\n<\/div>\n\n\n\n
    \n
    Medicinal chemistry<\/strong> <\/h5>\n
      \n
    • Path and progression to clinical quality compounds<\/li>\n
    • Hit identification \u2022 Hit to lead \u2022 Lead optimisation \u2022 Candidate selections<\/li>\n
    • Multiple target classes \u2022  Triage strategies \u2022 Screening strategies<\/li>\n
    • Prioritisation of series<\/li>\n<\/ul>\n<\/div>\n<\/div>\n\n\n\n
      \n
      \n
      Drug design principles<\/strong><\/h5>\n
        \n
      • Use of current physicochemical properties and molecular descriptors in drug design<\/li>\n
      • In silico<\/em> methods and data visualisation \u2022 SAR \u2022 Iterative and multi-parameter optimisation<\/li>\n<\/ul>\n<\/div>\n\n\n\n
        \n
        Tools, Modalities and DMPK<\/strong><\/h5>\n
          \n
        • Protein-protein interactions<\/li>\n
        • Chemical tools & probes \u2022 Large (bRo5) and small molecules (Ro5) \u2022 conjugates \u2022 mono- and multivalent ligands  <\/li>\n
        • Covalently bound and non-covalently bound inhibitors \u2022 Intracellular and extracellular targets<\/li>\n
        • DMPK profiling and interpretation. Assessment of routes of administration<\/li>\n<\/ul>\n<\/div>\n<\/div>\n\n\n\n
          \n
          \n
          Synthetic chemistry <\/strong><\/h5>\n
            \n
          • Route planning and synthesis<\/li>\n
          • Array design<\/li>\n
          • Large and small scale route design of complex molecules<\/li>\n
          • Work with CROs to synthesise compounds<\/li>\n<\/ul>\n<\/div>\n\n\n\n
            \n
            Patents & Due diligence<\/strong><\/h5>\n
              \n
            • Strategy<\/li>\n
            • Scientific content<\/li>\n
            • Analysis<\/li>\n
            • Detailed assessment of projects<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n
              <\/div>\n\n\n\n
              \"\"<\/figure>
              \n
              High quality tailored reporting output<\/strong><\/span><\/h5>\n
                \n
              • Detailed reports <\/span><\/span><\/li>\n
              • Presentations\u200b<\/span><\/li>\n
              • Discussion and collaborations<\/span><\/li>\n
              • Multiple approaches with prioritisation<\/span><\/span><\/li>\n
              • Literature analyses<\/span><\/span><\/li>\n
              • Screening cascades<\/span><\/li>\n
              • Identify the best experiments to undertake<\/span><\/span><\/li>\n
              • Patent assessment and molecule analysis<\/span><\/li>\n<\/ul>\n<\/div><\/div>\n\n\n\n\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"plain-container","ast-site-content-layout":"normal-width-container","site-content-style":"unboxed","site-sidebar-style":"unboxed","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"disabled","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"class_list":["post-24","page","type-page","status-publish","hentry"],"yoast_head":"\nMedchem and drug discovery consultancy – RGDscience Ltd<\/title>\n<meta name=\"description\" content=\"We consult in drug discovery and medicinal chemistry - working with many institutions, including academia, biotechs and pharma.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.rgdscience.com\/index.php\/consultancy\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Medchem and drug discovery consultancy – RGDscience Ltd\" \/>\n<meta property=\"og:description\" content=\"We consult in drug discovery and medicinal chemistry - working with many institutions, including academia, biotechs and pharma.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.rgdscience.com\/index.php\/consultancy\/\" \/>\n<meta property=\"article:modified_time\" content=\"2026-05-01T17:47:26+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.rgdscience.com\/wp-content\/uploads\/2024\/10\/Slide16.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1280\" \/>\n\t<meta property=\"og:image:height\" content=\"720\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Estimated reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.rgdscience.com\\\/index.php\\\/consultancy\\\/\",\"url\":\"https:\\\/\\\/www.rgdscience.com\\\/index.php\\\/consultancy\\\/\",\"name\":\"Medchem and drug discovery consultancy – RGDscience Ltd\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.rgdscience.com\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/www.rgdscience.com\\\/index.php\\\/consultancy\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/www.rgdscience.com\\\/index.php\\\/consultancy\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.rgdscience.com\\\/wp-content\\\/uploads\\\/2024\\\/10\\\/Slide16.jpg\",\"datePublished\":\"2019-09-17T13:23:12+00:00\",\"dateModified\":\"2026-05-01T17:47:26+00:00\",\"description\":\"We consult in drug discovery and medicinal chemistry - 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