selective avb3 antagonist

/ Medicinal Chemistry Consultancy / By

This work could significantly further our understanding of integrin signalling. It will be very interesting to observe if this is shown for the other integrin proteins.

Novel Pure αVβ3 Integrin Antagonists That Do Not Induce Receptor Extension, Prime the Receptor, or Enhance Angiogenesis at Low Concentrations. ACS Pharmacol. Transl. Sci. 2019, 2, 6, 387-401